Tradename | Company | Number | Date | Products |
---|---|---|---|---|
NEXLETOL | Esperion Therapeutics | N-211616 RX | 2020-02-21 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
NEXLIZET | Esperion Therapeutics | N-211617 RX | 2020-02-26 | 1 products, RLD, RS |
Expiration | Code | ||
---|---|---|---|
BEMPEDOIC ACID, NEXLETOL, ESPERION THERAPS INC | |||
2025-02-21 | NCE | ||
BEMPEDOIC ACID / EZETIMIBE, NEXLIZET, ESPERION THERAPS INC | |||
2025-02-21 | NCE |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | 5 | 1 | — | 6 |
Acute coronary syndrome | D054058 | EFO_0005672 | — | — | — | — | 1 | — | 1 |
St elevation myocardial infarction | D000072657 | — | — | — | — | — | 1 | — | 1 |
Non-st elevated myocardial infarction | D000072658 | — | — | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypercholesterolemia | D006937 | — | — | — | 9 | 5 | — | — | 14 |
Hyperlipidemias | D006949 | EFO_0003774 | E78.5 | 1 | 2 | 4 | — | 1 | 8 |
Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | 5 | — | — | 5 |
Hyperlipoproteinemias | D006951 | — | — | — | — | 3 | — | — | 3 |
Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | 3 | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 2 | — | — | — | 2 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | 2 | — | — | — | 2 |
Dyslipidemias | D050171 | — | — | 1 | 1 | — | — | — | 2 |
Hypertension | D006973 | EFO_0000537 | I10 | — | 1 | — | — | — | 1 |
Hypertriglyceridemia | D015228 | EFO_0004211 | — | — | 1 | — | — | — | 1 |
Hyperlipoproteinemia type ii | D006938 | EFO_0004911 | E78.00 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | — | 1 | 1 |
Drug common name | Bempedoic acid |
INN | bempedoic acid |
Description | Bempedoic acid is an alpha,omega-dicarboxylic acid that is pentadecanedioic acid which is substituted by methyl groups groups at positions 2 and 14, and by a hydroxy group at position 8. It is a drug used for the treatment of high LDL cholesterol, which is sometimes referred to as 'bad cholesterol'. It has a role as an antilipemic drug, an EC 2.3.3.8 (ATP citrate synthase) inhibitor and a prodrug. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CC(C)(CCCCCC(O)CCCCCC(C)(C)C(=O)O)C(=O)O |
PDB | — |
CAS-ID | 738606-46-7 |
RxCUI | — |
ChEMBL ID | CHEMBL3545313 |
ChEBI ID | — |
PubChem CID | 10472693 |
DrugBank | DB11936 |
UNII ID | 1EJ6Z6Q368 (ChemIDplus, GSRS) |